Reaktion #5433

Reaktionsgleichung

benzothiophene-2-carboxylic acid chloride

anilin

water

→

benzothiophene-2-carboxanilide

Ausbeute 77.0%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwhen the addition
2. 2
   Filtrationhas settled out is filtered off with suction
3. 3
   Waschenwashed twice with water
4. 4
   Sonstigedried

Vorschrift

To 8 g (0.0407 mol) of benzothiophene-2-carboxylic acid chloride in 150 ml of toluene there are added with stirring at room temperature 7.6 g (0.0814 mol) of anilin, then, when the addition is complete, the mixture is stirred for 5 hours at 50° C., the reaction mixture is then poured into water, and precipitate which has settled out is filtered off with suction, washed twice with water and dried. 7.9 g (77% of theory) of benzothiophene-2-carboxanilide of melting point 188° C. are obtained. ##STR10##

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