Reaktion #542618

Reaktionsgleichung

3-chloro-4-hydroxy-benzoic acid

cis-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline

2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate

→

title compound

Ausbeute 42.0%

(3-Chloro-4-hydroxy-phenyl)-(cis-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-methanone

Ausbeute 42.0%

Reaktionsbedingungen

Vorschrift

The title compound is prepared from 3-chloro-4-hydroxy-benzoic acid and cis-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline following a procedure analogous to that described in Example 1 [2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate is used]. Yield: 42% of theory; LC (method 4): tR=1.98 min; Mass spectrum (ESI+): m/z=342/344 (Cl) [M+H]+.

Quelle