Reaktion #54251

ord-bee6e3df24624b6d98464e0a489e9362

Reaktionsgleichung

CC(C)C=NC(c1ccccc1)c1ccccc1
isobutylidenebenzhydrylamine
O=[PH2]O
Hypophosphorous acid
→
CC(C)C(NC(c1ccccc1)c1ccccc1)P(O)O
1-benzhydrylamino-2-methylpropanephosphonous acid

Edukte

—
41.3
CC(C)C=NC(c1ccccc1)c1ccccc1
isobutylidenebenzhydrylamine
O=[PH2]O
Hypophosphorous acid

Reagenzien

Keine

Lösungsmittel

CCO
ethanol
CCO
ethanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeAn exothermic reaction
  2. 2
    Filtrationthe reaction was filtered
  3. 3
    Sonstigethe white solid dried in vacuo

Vorschrift

Hypophosphorous acid (100%, 15.8 parts) dissolved in absolute ethanol was added to a stirred solution of 41.3 parts isobutylidenebenzhydrylamine in absolute ethanol. An exothermic reaction occurred. After standing one hour the reaction was filtered and the white solid dried in vacuo. There was obtained DL-1-benzhydrylamino-2-methylpropanephosphonous acid, melting point 191° (dec.).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04147780uspto-grants-1979_04