Reaktion #54241

Reaktionsgleichung

cyclohexa(b)furan-4-one

potassium cyanide

ammonium carbonate

water

hydrochloric acid

→

spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was cooled
2. 2
   SonstigeThe precipitated product was isolated by filtration
3. 3
   Sonstigerecrystallized from ethanol

Vorschrift

A mixture of 2.7 g of cyclohexa(b)furan-4-one (Bull. Soc. Chim. Fr., 1967, 2796), 1.95 g of potassium cyanide and 9.6 g of powdered ammonium carbonate were heated with 40 ml of 95% aqueous ethanol at 110°-120° C. in a steel bomb for 16 hours. The reaction mixture was cooled, diluted with 200 ml of water, and acidified with 12 N hydrochloric acid. The precipitated product was isolated by filtration and recrystallized from ethanol to give 1.73 g of spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione, mp 245°-248° C.

Quelle