Reaktion #54238

Reaktionsgleichung

2-Bromo-3-phenyl-butyrophenone

1,2,4-triazole

potassium carbonate

→

title compound

2-(1,2,4-Triazol-1-yl)-3-phenylbutyrophenone

Lösungsmittel

methyl ethyl ketone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe solution was filtered
2. 2
   Sonstigethe solvent removed in vacuo
3. 3
   SonstigeRecrystallisation of the residue from ethanol/petroleum ether (60°-80°)

Vorschrift

2-Bromo-3-phenyl-butyrophenone (0.02 mol), 1,2,4-triazole (0.02 mol) and potassium carbonate (0.04 mol) were refluxed in methyl ethyl ketone (100 ml) for 36 hours. After cooling to room temperature, the solution was filtered and the solvent removed in vacuo. Recrystallisation of the residue from ethanol/petroleum ether (60°-80°) gave the title compound as a colourless solid, m.p. 166°-8°.

Quelle