Reaktion #54153

Reaktionsgleichung

4-diethylaminosalicylaldehyde

dimethyl 1,3-acetone dicarboxylate

→

methyl 7-diethylamino-3coumarinoylacetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux on a steam bath for 2 hours
2. 2
   TemperaturAfter chilling in the freezer
3. 3
   Sonstigethe product was collected
4. 4
   Sonstigerecrystallized from a mixture of alcohol and acetonitrile

Vorschrift

A solution of 1.93 g 4-diethylaminosalicylaldehyde, 1.80 g. dimethyl 1,3-acetone dicarboxylate in 10 ml. alcohol containing 10 drops piperidine was heated under reflux on a steam bath for 2 hours. After chilling in the freezer, the product was collected and recrystallized from a mixture of alcohol and acetonitrile. Yield 2.6 g (82%).

Quelle