Reaktion #54048

ord-cbfc5c9e672e4166b815af582066c4ec

Reaktionsgleichung

COc1ccccc1-c1ccc2c(c1)C(CSc1ccc3ccccc3c1)=CC(C)(C)N2
6-(2-Methoxyphenyl)-2,2-dimethyl-4-(naphthalen-2-ylsulfanylmethyl)-1,2-dihydroquinoline
COc1ccccc1-c1ccc2c(c1)C(CBr)=CC(C)(C)N2
4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline
O=C([O-])[O-].[K+].[K+]
potassium carbonate
Sc1ccc2ccccc2c1
2-naphthalenethiol
→
COc1ccccc1-c1ccc2c(c1)C(CNc1ccccc1)=CC(C)(C)N2
title compound
COc1ccccc1-c1ccc2c(c1)C(CNc1ccccc1)=CC(C)(C)N2
[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine

Edukte

COc1ccccc1-c1ccc2c(c1)C(CSc1ccc3ccccc3c1)=CC(C)(C)N2
6-(2-Methoxyphenyl)-2,2-dimethyl-4-(naphthalen-2-ylsulfanylmethyl)-1,2-dihydroquinoline
COc1ccccc1-c1ccc2c(c1)C(CBr)=CC(C)(C)N2
4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline
O=C([O-])[O-].[K+].[K+]
potassium carbonate
Sc1ccc2ccccc2c1
2-naphthalenethiol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

6-(2-Methoxyphenyl)-2,2-dimethyl-4-(naphthalen-2-ylsulfanylmethyl)-1,2-dihydroquinoline 100 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline, 80 mg of potassium carbonate, and 42 mg of 2-naphthalenethiol reacted to give 8 mg of the title compound as an oil.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06858627B2uspto-grants-2005_02