Reaktion #539899

ord-9f709825513e434b91d753863e799092

Reaktionsgleichung

NNC(=O)c1ccc2occc2c1
1-benzofuran-5-carbohydrazide
COc1ccc(CCC(=O)O)cc1
3-(4-methoxyphenyl)propionic acid
COc1ccc(CCc2nnc(-c3ccc4occc4c3)o2)cc1
title compound
Ausbeute 53.0%
COc1ccc(CCc2nnc(-c3ccc4occc4c3)o2)cc1
2-(1-benzofuran-5-yl)-5-[2-(4-methoxyphenyl)ethyl]-1,3,4-oxadiazole
Ausbeute 53.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In the same manner as in Example 14 and using 1-benzofuran-5-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 3-(4-methoxyphenyl)propionic acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 53%) was obtained as colorless crystals.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08492378B2uspto-grants-2013_07