Reaktion #539272

Reaktionsgleichung

(R)-4-phenyloxazolidin-2-one

HCl

potassium carbonate

cyclohexane-1,2-diamine

4-bromobenzene-1,2-diamine

→

(R)-3-(1H-benzo[d]imidazol-6-yl)-4-phenyloxazolidin-2-one

Lösungsmittel

formic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe compound was synthesized

Vorschrift

The compound was synthesized starting from (R)-4-phenyloxazolidin-2-one (1 equiv., 0.163 g, 1 mmol), 4-bromobenzene-1,2-diamine (1 equiv., 0.187 g, 1 mmol), copper(I) iodide (0.1 equiv., 0.019 g, 0.1 mmol), potassium carbonate (2 equiv., 0.276 g, 2 mmol), cyclohexane-1,2-diamine (0.1 equiv., 0.012 mL, 0.1 mmol), 5N HCl (3.4 mL), formic acid (0.343 mL) as described in method 5 step D.

Quelle