Reaktion #538555

Reaktionsgleichung

3-(4-fluoro-phenyl)-pyridin-2-ylamine

ethoxycarbonyl isothiocyanate

→

title compound

N-(3-(4-Fluoro-phenyl)-pyridin-2-yl)-N′-ethoxycarbonyl-thiourea

Lösungsmittel

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated
2. 2
   Sonstigethe residue was used for the next step without purification

Vorschrift

To a solution of 3-(4-fluoro-phenyl)-pyridin-2-ylamine (200 mg, 1.06 mmol) in dioxane (10 mL) was added ethoxycarbonyl isothiocyanate (141 μL, 1.17 mmol) and stirred at room temperature for 12 hours. The solvent was evaporated and the residue was used for the next step without purification. The title compound was obtained as a light yellow solid (340 mg, 100%).

Quelle