Reaktion #538445

Reaktionsgleichung

toluene-4-sulfonic acid 3-trifluoromethyl-phenyl ester

ethynyl-cyclohexane

→

1-Cyclohexylethynyl-3-trifluoromethyl-benzene

Lösungsmittel

heptane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeyield (82 mg, 65%)

Vorschrift

This product was prepared from toluene-4-sulfonic acid 3-trifluoromethyl-phenyl ester and ethynyl-cyclohexane following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane; yield (82 mg, 65%); δH (CDCl3): 7.67 (s, 1H), 7.61-7.7.49 (m, 2H), 7.46-7.37 (m, 1H), 2.70-2.52 (m, 1H), 2.04-1.30 (m, 10H); LCMS m/z: 252.

Quelle