Reaktion #53666

Reaktionsgleichung

5-amino-N-tert-butoxycarbonyl-3-methyl-1H-indazole

tetrahydrofuran

3,4-dichlorobenzenesulfonyl chloride

→

N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-3,4-dichlorobenzenesulfonamide

Ausbeute 43.4%

Lösungsmittel

triethylamine

Reaktionsbedingungen

Vorschrift

N-(N-tert-Butoxycarbonyl-3-methyl-1H-indazol-5-yl)-3,4-dichlorobenzenesulfonamide can be obtained as described in Example 1 from 1 g of 5-amino-N-tert-butoxycarbonyl-3-methyl-1H-indazole, 50 ml of tetrahydrofuran, 1.15 ml of triethylamine and 1.1 g of 3,4-dichlorobenzenesulfonyl chloride. 0.8 g of N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-3,4-dichlorobenzenesulfonamide is thus obtained in the form of a white solid melting at 171° C.

Quelle