Reaktion #53429

Reaktionsgleichung

compound

1-Allyloxy-2-chloromethylbenzene

ammonia

→

(2-Allyloxy-benzyl)amine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction mixture is evaporated in vacuo
2. 2
   Sonstigethe mixture is evaporated again
3. 3
   Extraktionextracted several times with water
4. 4
   SonstigeThe aqueous phase is evaporated to a very great extent
5. 5
   Sonstigean oil being obtained which
6. 6
   Sonstigecrystallizes on standing

Vorschrift

3.0 g (16.4 mmol) of the compound from Example I are boiled under reflux for 17 hours in 250 ml of a saturated methanolic ammonia solution. The reaction mixture is evaporated in vacuo, the residue is taken up in methanol and the mixture is evaporated again; this process is repeated a few times. The crude product is taken up in dichloromethane and extracted several times with water. The aqueous phase is evaporated to a very great extent, an oil being obtained which crystallizes on standing.

Quelle