Reaktion #53406

Reaktionsgleichung

Amine

4-(4-Methoxyphenyl)butylamine

HBr

→

4

Ausbeute 90.0%

4-(4-Hydroxyphenyl)butylamine Hydrobromide

Ausbeute 90.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigefor 3 h
2. 2
   Sonstigeargon was bubbled through the solution
3. 3
   Sonstigethe solvent was evaporated under reduced pressure
4. 4
   TrocknenThe solid residue was dried above KOH

Vorschrift

Amine 3 (2.32 g, 0.012 mol) was stirred in boiling 48% HBr (50 mL) for 3 h. After the reaction was completed, argon was bubbled through the solution and the solvent was evaporated under reduced pressure. The solid residue was dried above KOH to provide 3.1 g (90%) of 4. APCI MS m/z=166[C10H15NO+H]+.

Quelle