Reaktion #533879

ord-46f7845c85f246f49a355a5e54230598

Reaktionsgleichung

CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)O
lys(Boc)
O=C(O)C(F)(F)F
TFA
→
NCCCC[C@H](N)C(=O)O
Lys

Edukte

CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)O
lys(Boc)
O=C(O)C(F)(F)F
TFA

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

A portion of 40.0 mg (18.9 μmol, 1.00 eq) of PMB-protected (Trimer-lys(Boc))2-TEGDA OMe was treated with hot TFA according to general procedure E to yield (Trimer-Lys)2-TEGDA as a colorless solid. Yield: 26.0 mg (18.3 μmol, 97%).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08481494B2uspto-grants-2013_07