Reaktion #53376

ord-c8cc28f18c9443a2981ce665cdcd0af1

Reaktionsgleichung

COc1ccc(CCCN=[N+]=[N-])cc1
azide
COc1ccc(CCCN=[N+]=[N-])cc1
3-(4-Methoxyphenyl)propylazide
[Al+3].[H-].[H-].[H-].[H-].[Li+]
LAH
→
COc1ccc(CCCN)cc1
Amine
COc1ccc(CCCN)cc1
3-(4-Methoxyphenyl)propylamine

Edukte

COc1ccc(CCCN=[N+]=[N-])cc1
azide
COc1ccc(CCCN=[N+]=[N-])cc1
3-(4-Methoxyphenyl)propylazide
[Al+3].[H-].[H-].[H-].[H-].[Li+]
LAH

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Amine 13 was prepared as described in procedure A from azide 12 (5.2 g, 0.027 mol) and LAH (26 ml of 1 M solution in THF).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06858614B2uspto-grants-2005_02