Reaktion #53220

Reaktionsgleichung

4-fluoronitrobenzene

N,N-dimethylethylene-diamine

hydrochloric acid

→

4-(2-dimethylamino-ethylamino)-nitrobenzene

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   WaschenThe reaction solution is washed with ethyl acetate
2. 2
   SonstigeThen the aqueous phase is combined with 4 N sodium hydroxide solution until an alkaline reaction
3. 3
   Sonstigeis obtained
4. 4
   Extraktionextracted with ethyl acetate

Vorschrift

2.2 ml of (20 mmol) of 4-fluoronitrobenzene and 2.6 ml (24 mmol) of N,N-dimethylethylene-diamine are heated in 10 ml of ethanol at 120° C. in a microwave oven for 1.5 hours. Then 50 ml of 1 N hydrochloric acid are added. The reaction solution is washed with ethyl acetate. Then the aqueous phase is combined with 4 N sodium hydroxide solution until an alkaline reaction is obtained and extracted with ethyl acetate.

Quelle