Reaktion #53215

Reaktionsgleichung

4-(2-bromoethyloxy)-nitrobenzene

dimethylamine

→

4-(2-dimethylaminoethyloxy)-nitrobenzene

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter removal of the solvent in vacuo the residue
2. 2
   Extraktionextracted with dichloromethane
3. 3
   SonstigeThe organic phase is dried
4. 4
   Einengenconcentrated by evaporation

Vorschrift

4.9 g (20 mmol) of 4-(2-bromoethyloxy)-nitrobenzene and 2.7 g (60 mmol) of dimethylamine in 50 ml of dimethylformamide are heated to 100° C. for 24 hours in a bomb tube. After removal of the solvent in vacuo the residue is taken up in water and extracted with dichloromethane. The organic phase is dried and concentrated by evaporation.

Quelle