Reaktion #53194

ord-4bb65f27294d48a2903d32dd2df8651a

Reaktionsgleichung

CC(=O)N1C(=O)C(=C(Cl)c2cccc(Cl)c2)c2cc([N+](=O)[O-])ccc21

1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone

4-dimethylaminomethyl-aniline

sodium hydroxide

→

$CN(C)Cc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2cccc(Cl)c2)cc1$

(Z)-3-[1-(4-dimethylaminomethyl-phenylamino)-1-(3-chlorophenyl)-methylidene]-5-nitro-2-indolinone

Edukte

1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone

4-dimethylaminomethyl-aniline

sodium hydroxide

Reagenzien

Keine

Lösungsmittel

DMF

methanol

Reaktionsbedingungen

Detaillierte Bedingungen

See reaction.notes.procedure_details.

Vorschrift

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06855710B2uspto-grants-2005_02