Reaktion #531834

Reaktionsgleichung

N-butyl-N-methylamine

diisopropylcarbodiimide

diisopropylcarbodiimide

→

guanidine

Ausbeute 100.0%

1-Butyl-2,3-diisopropyl-1-methylguanidine

Ausbeute 100.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturat reflux for 3 hours
3. 3
   Einengenis concentrated at 60° C. under 5 mbar for 2 hours
4. 4
   Sonstigeto give 40 g of a colorless and virtually odorless liquid of low viscosity, which

Vorschrift

A mixture of 32.68 g of N-butyl-N-methylamine (0.375 mol) and 23.66 g of diisopropylcarbodiimide (0.1875 mol) is heated at reflux for 3 hours. GC analysis then shows a conversion of more than 99.5% of the diisopropylcarbodiimide. The final mixture, which is colorless, is concentrated at 60° C. under 5 mbar for 2 hours, to give 40 g of a colorless and virtually odorless liquid of low viscosity, which corresponds to the expected guanidine (100% yield).

Quelle