Reaktion #531651

ord-f840c91376c24a519f9115c0519d4b2a

Reaktionsgleichung

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(Sc2ccc(Cl)cc2)nc1
1-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea
Cl
HCl
→
Cl.O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(Sc2ccc(Cl)cc2)nc1
1-(2,6-DICHLOROBENZOYL)-3-(6-(4-CHLOROPHENYLTHIO)-3-PYRIDINYL)UREA, HYDROCHLORIDE SALT

Edukte

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(Sc2ccc(Cl)cc2)nc1
1-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea
Cl
HCl

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    TemperaturThe reaction mixture was cooled
  2. 2
    Sonstigethe product separated by filtration, yield 1.5 grams, m.p., 214°-217° C.

Vorschrift

1-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea (2.0 grams) was refluxed in 100 ml. of concentrated HCl (37%) for 4 hours. The reaction mixture was cooled and the product separated by filtration, yield 1.5 grams, m.p., 214°-217° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04264605uspto-grants-1981_04