Reaktion #53155

ord-02e67ea4537a43aabac237d3c6c200af

Reaktionsgleichung

CCOC(=C1C(=O)Nc2ccc([N+](=O)[O-])cc21)c1ccccc1
3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
CCOC(=O)C1CCN(Cc2ccc(N)cc2)CC1
4-(4-ethoxycarbonyl-piperidinomethyl)-aniline
→
CCOC(=O)C1CCN(Cc2ccc(N/C(=C3\C(=O)Nc4ccc([N+](=O)[O-])cc43)c3ccccc3)cc2)CC1
(Z)-3-{1-[4-(4-ethoxycarbonyl-piperidinomethyl)-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone

Edukte

CCOC(=C1C(=O)Nc2ccc([N+](=O)[O-])cc21)c1ccccc1
3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
CCOC(=O)C1CCN(Cc2ccc(N)cc2)CC1
4-(4-ethoxycarbonyl-piperidinomethyl)-aniline

Reagenzien

Keine

Lösungsmittel

CN(C)C=O
DMF

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogously to Example 89 from 3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-(4-ethoxycarbonyl-piperidinomethyl)-aniline in DMF.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06855710B2uspto-grants-2005_02