Reaktion #53079

ord-3e5d2401b98d4edba65671d88f44fe5d

Reaktionsgleichung

COC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1ccc([N+](=O)[O-])cc1
4-nitroaniline
N
ammonia
→
O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1ccc([N+](=O)[O-])cc1)c1ccccc1
(Z)-3-[1-(4-nitrophenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone

Edukte

COC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1ccc([N+](=O)[O-])cc1
4-nitroaniline
N
ammonia

Reagenzien

Keine

Lösungsmittel

CN(C)C=O
DMF

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogously to Example 77 from 1-acetyl-3-(1-methoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-nitroaniline in DMF and subsequent treatment with methanolic ammonia.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06855710B2uspto-grants-2005_02