Reaktion #529779

Reaktionsgleichung

2,6-naphthalenedicarboxylic acid dichloride

methylene chloride

triethylamine

1,1,1-trifluoro-2-octanol

dimethylformamide

methylene chloride

→

4-n-octyloxycarbonyl-4'-hydroxybiphenyl

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooling

Vorschrift

Optically active 1,1,1-trifluoro-2-octanol (0.3 g), dimethylformamide (0.2 g) and triethylamine (0.18 g) were dissolved in methylene chloride (20 ml). To this solution was added in small portions a solution of 2,6-naphthalenedicarboxylic acid dichloride (0.8 g) obtained in the step 2) of Example 7 in methylene chloride (50 ml) under ice-cooling, and the mixture was stirred for about 20 hours. Next, 4-n-octyloxycarbonyl-4'-hydroxybiphenyl (0.55 g) obtained in the step 1) was dissolved in methylene chloride (30 ml) and added in small portions to the reaction mixture. The resulting mixture was stirred for about 20 hours.

Quelle