Reaktion #529776

Reaktionsgleichung

hydrochloric acid

Nonanoyl chloride

dimethylaminopyridine

4'-Hydroxybiphenyl-4-carboxylic acid

→

titled compound

Ausbeute 86.3%

4'-n-nonanoyloxybiphenyl-4-carboxylic acid

Ausbeute 86.3%

Lösungsmittel

dichloromethane

triethylamine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe organic layer was separated in a separating funnel
2. 2
   SonstigeThe solvent was removed by evaportaion
3. 3
   Sonstigethe residue was dried
4. 4
   Waschenafter washing with n-hexane

Vorschrift

4'-Hydroxybiphenyl-4-carboxylic acid (3.5 g) and triethylamine (2.4 g) were dissolved in dichloromethane (30 ml). Nonanoyl chloride (4.3 g) and dimethylaminopyridine (0.2 g) were added to the solution, and the mixture was stirred at room temperature for about 20 hours. Dilute hydrochloric acid was added thereto, and the organic layer was separated in a separating funnel. The solvent was removed by evaportaion, and the residue was dried after washing with n-hexane to give the titled compound (5 g).

Quelle