Reaktion #52800

Reaktionsgleichung

5-chlorosulfonyl-2-oxindole

isopropylamine

pyridine

→

5-isopropylaminosulfonyl-2-oxindole

Ausbeute 45.5%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solid was collected by vacuum filtration
2. 2
   Waschenslurry-washed with hot ethanol
3. 3
   Temperaturcooled
4. 4
   Filtrationcollected by vacuum filtration and vacuum
5. 5
   Sonstigedried at 40° C.

Vorschrift

A suspension of 3 g of 5-chlorosulfonyl-2-oxindole, 1.15 g of isopropylamine and 1.2 mL of pyridine in 50 mL of dichloromethane was stirred at room temperature for 4 hours at which time a white solid was present. The solid was collected by vacuum filtration, slurry-washed with hot ethanol, cooled, collected by vacuum filtration and vacuum dried at 40° C. to give 1.5 g (45%) of 5-isopropylaminosulfonyl-2-oxindole.

Quelle