Reaktion #52591

Reaktionsgleichung

5-chlorosulfonyl-2-oxindole

morpholine

→

5-(morpholinosulfonyl)-2-oxindole

Ausbeute 74.9%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe white precipitate was collected by vacuum filtration
2. 2
   Waschenwashed with ethyl acetate and hexane
3. 3
   Sonstigedried under vacuum at 40° C. overnight

Vorschrift

A suspension of 2.3 g of 5-chlorosulfonyl-2-oxindole and 2.2 g of morpholine in 50 mL of dichloromethane was stirred at room temperature for 3 hours. The white precipitate was collected by vacuum filtration, washed with ethyl acetate and hexane and dried under vacuum at 40° C. overnight to give 2.1 g (74% yield) of 5-(morpholinosulfonyl)-2-oxindole.

Quelle