Reaktion #52585

Reaktionsgleichung

5-Fluoroisatin

→

title compound

5-Fluoro-2-oxindole

Lösungsmittel

hydrazine hydrate

—

ice water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturrefluxed for 1.0 hr
2. 2
   SonstigeThe reaction mixtures
3. 3
   FiltrationThe precipitate was then filtered
4. 4
   Waschenwashed with water
5. 5
   Sonstigedried in a vacuum oven

Vorschrift

5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.

Quelle