Reaktion #52568

Reaktionsgleichung

Hünig's base

potassium cyanide

4-methylene-3-oxabicyclo[3.2.1]octan-2-one

→

ethyldiisopropyl-ammonium

4-hydroxybicyclo[3.2.1]oct-3-en-2-one

Lösungsmittel

acetonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationSolid components (potassium salts) are filtered off
2. 2
   Sonstigethe filtrate is evaporated to dryness

Vorschrift

Analogously to Example P1, 1.38 g (10 mmol) of 4-methylene-3-oxabicyclo[3.2.1]octan-2-one are stirred over a period of 12 hours in the presence of 1.29 g (10 mmol) of Hünig's base and 0.13 g of potassium cyanide in 10 ml of acetonitrile. Solid components (potassium salts) are filtered off and the filtrate is evaporated to dryness to yield the ethyldiisopropyl-ammonium salt of 4-hydroxybicyclo[3.2.1]oct-3-en-2-one in the form of a resin.

Quelle