Reaktion #523561

Reaktionsgleichung

diphenylacetonitrile

phosphorus pentachloride

→

α-chlorodiphenylacetonitrile

Ausbeute 91.7%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated at 125° for 4 hours
2. 2
   Extraktionextracted with ether
3. 3
   WaschenThe combined ether extracts are washed with 10% hydrochloric acid, saturated aqueous sodium bicarbonate solution
4. 4
   Trocknendried over magnesium sulfate
5. 5
   SonstigeThe solvent is evaporated

Vorschrift

A mixture of 25 g (0.13 m) of diphenylacetonitrile and 27 g (0.13 m) of phosphorus pentachloride is heated at 125° for 4 hours. The reaction mixture is poured into water and extracted with ether. The combined ether extracts are washed with 10% hydrochloric acid, saturated aqueous sodium bicarbonate solution and dried over magnesium sulfate. The solvent is evaporated to give 27 g of crude α-chlorodiphenylacetonitrile.

Quelle