Reaktion #5227

Reaktionsgleichung

4-Chloro-furo[3,4-c]quinolin-3(1H)-one

sodium acetate

→

Furo[3,4-c]quinolin-3(1H)-one

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter filtration through celite
2. 2
   Sonstigethe solvent was removed in vacuo
3. 3
   FiltrationAfter filtration the solvent
4. 4
   Sonstigewas removed in vacuo

Vorschrift

A mixture of 4-Chloro-furo[3,4-c]quinolin-3(1H)-one (500 mg), 10% Palladium on carbon (100 mg) and sodium acetate (500 mg) in 20 mL of acetic acid was hydrogenated at atmospheric pressure for 2 h. After filtration through celite, the solvent was removed in vacuo, and the residue was taken up in methylene chloride. After filtration the solvent was removed in vacuo to afford Furo[3,4-c]quinolin-3(1H)-one as a solid.

Quelle