Reaktion #518601

ord-0bf4edad633e4a898e3af4f4cb85a9d6

Reaktionsgleichung

O=C(Cl)C12CC3CC(O)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-hydroxyadamantane
CN(C)C
trimethylamine
C[Si](C)(C)Cl
trimethylsilyl chloride
→
C[Si](C)(C)OC12CC3CC(C(=O)Cl)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-trimethylsiloxyadamantane

Edukte

O=C(Cl)C12CC3CC(O)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-hydroxyadamantane
CN(C)C
trimethylamine
C[Si](C)(C)Cl
trimethylsilyl chloride

Reagenzien

Keine

Lösungsmittel

ClCCl
methylene chloride

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeReaction
  2. 2
    Sonstigewas carried out at room temperature

Vorschrift

The 1,3-dichloroformyl-5-hydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature to obtain 1,3-dichloroformyl-5-trimethylsiloxyadamantane.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06660450B2uspto-grants-2003_12