Reaktion #51761

ord-c77133d2549b45b9a0778b01884be175

Reaktionsgleichung

CC(C)(C)c1ccc([N+](=O)[O-])c(NC(=O)C(F)(F)F)c1
N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide
O=C([O-])[O-].[K+].[K+]
potassium carbonate
→
CC(C)(C)c1ccc([N+](=O)[O-])c(N)c1
title compound
CC(C)(C)c1ccc([N+](=O)[O-])c(N)c1
5-tert-Butyl-2-nitro-phenylamine

Edukte

CC(C)(C)c1ccc([N+](=O)[O-])c(NC(=O)C(F)(F)F)c1
N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide
O=C([O-])[O-].[K+].[K+]
potassium carbonate

Reagenzien

Keine

Lösungsmittel

CO
MeOH

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe crude product was used without any purification

Vorschrift

The title compound was prepared as outlined in Example PP-1 from N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide (prepared in Example OO-2; 248 g, 855 mmol), MeOH (500 mL), and 7% aqueous potassium carbonate solution. The crude product was used without any purification. MS(APCI): 195 (M+H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06852711B2uspto-grants-2005_02