Reaktion #517227

Reaktionsgleichung

Diphenylphosphine

methyl 2-trifluoromethanesulfonyloxybenzoate

triethylamine

→

Methyl 2-diphenylphosphinobenzoate

Lösungsmittel

MeCN

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeinstantly giving a red coloration
2. 2
   TemperaturThe solution was heated
3. 3
   Temperaturat reflux under nitrogen for 17 hours
4. 4
   Temperaturto cool

Vorschrift

Diphenylphosphine (0.94 mL, 5.40 mmol, 1 eq) was added to a stirred solution of methyl 2-trifluoromethanesulfonyloxybenzoate (1.531 g, 5.39 mmol, 1 eq), triethylamine (0.85 mL, 6.1 mmol, 1.1 eq) and palladium acetate (0.005 g, 0.02 mmol, 0.004 eq) in degassed MeCN (10 mL) instantly giving a red coloration. The solution was heated at reflux under nitrogen for 17 hours. The blood-red solution was allowed to cool and an aliquot taken for NMR analysis.

Quelle