Reaktion #517224

Reaktionsgleichung

Diphenylphosphine

methyl 2-trifluoromethanesulfonyloxy-1-naphthoate

triethylamine

→

Methyl 2-diphenylphosphino-1-naphthoate

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeinstantly giving a red coloration
2. 2
   TemperaturThe solution was heated
3. 3
   Temperaturat reflux under nitrogen for 17 hours
4. 4
   Temperaturto cool

Vorschrift

Diphenylphosphine (0.72 mL, 4.14 mmol, 1 eq) was added to a stirred solution of methyl 2-trifluoromethanesulfonyloxy-1-naphthoate (1.384 g, 4.14 mmol, 1 eq), triethylamine (0.64 mL, 4.59 mmol, 1.1 eq) and palladium acetate (0.005 g, 0.02 mmol, 0.005 eq) in degassed DMF (10 mL) instantly giving a red coloration. The solution was heated at reflux under nitrogen for 17 hours. The blood-red solution was allowed to cool and an aliquot taken for NMR analysis.

Quelle