Reaktion #515280

ord-d17f46fdca7e4c38bdbb6dec8bd36805

Reaktionsgleichung

C[C@H](NC(=O)Cc1cccc(Cl)c1)C(=O)O
3-chlorophenylacetyl alanine
C[C@H](NC(=O)Cc1cccc(Cl)c1)C(=O)O
N-(3-chlorophenylacetyl)alanine
CC1CCCC1O
2-methylcyclopentanol
→
CC1CCCC1OC(=O)[C@H](C)NC(=O)Cc1cccc(Cl)c1
title compound
CC1CCCC1OC(=O)[C@H](C)NC(=O)Cc1cccc(Cl)c1
N-[(3-chlorophenyl)acetyl]aianine 2-methylcyclopentyl Ester

Edukte

C[C@H](NC(=O)Cc1cccc(Cl)c1)C(=O)O
3-chlorophenylacetyl alanine
C[C@H](NC(=O)Cc1cccc(Cl)c1)C(=O)O
N-(3-chlorophenylacetyl)alanine
CC1CCCC1O
2-methylcyclopentanol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following General Procedure C above, and using N-(3-chlorophenylacetyl alanine (from Example D above) and 2-methylcyclopentanol (Aldrich) the title compound can be prepared. The reaction was monitored by tlc on silica gel and purification was by liquid chromatography using 3:7 EtOAc:hexane as the eluant.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06313152B1uspto-grants-2001_11