Reaktion #514865

ord-b2caa205f7d34fa1866af20e0e50dd4d

Reaktionsgleichung

Nc1ccccc1C(=O)Nc1cccc(OOCc2ccccc2)c1
N-(3-benzyloxyoxyphenyl)-2-aminobenzamide
O=C(Cl)C1CCN(c2ccncc2)CC1
N-(4-pyridyl)isonipecotoyl chloride
→
O=C(Nc1cccc(OCc2ccccc2)c1)c1ccccc1NC(=O)C1CCN(c2ccncc2)CC1
title compound
Ausbeute 164.8%
O=C(Nc1cccc(OCc2ccccc2)c1)c1ccccc1NC(=O)C1CCN(c2ccncc2)CC1
2-[[1-(4-Pyridyl)piperidin-4-ylcarbonyl]amino]-N-(3-benzyloxyphenyl)benzamide
Ausbeute 164.8%

Edukte

Nc1ccccc1C(=O)Nc1cccc(OOCc2ccccc2)c1
N-(3-benzyloxyoxyphenyl)-2-aminobenzamide
O=C(Cl)C1CCN(c2ccncc2)CC1
N-(4-pyridyl)isonipecotoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using the procedure described in Example 138, N-(3-benzyloxyoxyphenyl)-2-aminobenzamide (0.97 mmol) and N-(4-pyridyl)isonipecotoyl chloride (1.9 mmol), yielded 405 mg (82%) of the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06313122B1uspto-grants-2001_11