Reaktion #51459

Reaktionsgleichung

5-chlorocarbonylphthalid

dimethylamine

→

5-(N,N-dimethylcarbamyl)phthalid

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeTHF is evaporated off in vacuo
2. 2
   Sonstigeprecipitated crystals
3. 3
   Sonstigeare filtred off at 5° C.
4. 4
   Waschenwashed with water (100 ml)

Vorschrift

A solution of 5-chlorocarbonylphthalid (32 g, 0.16 mole) in THF (300 ml) is added to dimethylamine (40% v/v in water, 300 ml) and ice (100 g). The mixture is stirred for 1 hour. THF is evaporated off in vacuo and precipitated crystals are filtred off at 5° C. and washed with water (100 ml).

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