Reaktion #514129

Reaktionsgleichung

1-[2-(1-naphthyl)-2-hydroxyethyl]imidazole

thionyl chloride

→

1-[2-(1-naphthyl)-2-chloroethyl]imidazole hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThereafter, the reaction mixture is evaporated to dryness
2. 2
   workup.ADDITIONthe residue treated with ethyl acetate
3. 3
   Filtrationfiltered

Vorschrift

1-[2-(1-naphthyl)-2-hydroxyethyl]imidazole (2.0 g.) and 5 ml. of thionyl chloride are stirred at room temperature for 30 minutes. Thereafter, the reaction mixture is evaporated to dryness and the residue treated with ethyl acetate and filtered to yield 1-[2-(1-naphthyl)-2-chloroethyl]imidazole hydrochloride as a white solid.

Quelle