Reaktion #514125

Reaktionsgleichung

3-(1-methyl-3-nitro-4-pyrazolyl)-acrylic acid

sodium hydroxide

sodium

→

Sodium 3-(1-methyl-3-nitro-4-pyrazolyl)-acrylate

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe clear solution is evaporated to dryness
2. 2
   Sonstigethe residue is triturated with isopropanol
3. 3
   FiltrationAfter filtering off with suction
4. 4
   Waschenwashing with diethyl ether, there
5. 5
   Sonstigeare obtained 170 mg

Vorschrift

197 mg. 3-(1-methyl-3-nitro-4-pyrazolyl)-acrylic acid (prepared according to Example 1) are neutralized with a dilute aqueous solution of sodium hydroxide. The clear solution is evaporated to dryness and the residue is triturated with isopropanol. After filtering off with suction and washing with diethyl ether, there are obtained 170 mg. of the desired sodium salt; m.p. 306° (with foaming).

Quelle