Reaktion #51407

Reaktionsgleichung

cinnamoyl chloride

aniline

→

4-Phenyl-3,4-dihydrocarbostyril

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe title compound was purified by flash chromatography
2. 2
   Wascheneluting with CH2Cl2/EtOAc (4:1)

Vorschrift

4-Phenyl-3,4-dihydrocarbostyril (CAS# 4888-33-9) was prepared in two steps using the procedure described by Conley, R. T.; Knopka. W. N. J. Org. Chem. 1964, 29, 496-497. The starting materials for this preparation were cinnamoyl chloride (Aldrich) and aniline (Aldrich). The title compound was purified by flash chromatography eluting with CH2Cl2/EtOAc (4:1).

Quelle