Reaktion #51371

ord-185645bbd25a4e468a466d4b28ce013b

Reaktionsgleichung

O=C(O)Cc1cccs1
2-thiopheneacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
CCC(NC(=O)Cc1cccs1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1cccs1)C(=O)OCC(C)C
2-[(2-thienyl)acetamido]butyric acid iso-butyl ester

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigetic on silica gel and purification
  2. 2
    Filtrationwas by filtration

Vorschrift

Following General Procedure BI above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tic on silica gel and purification was by filtration as described in the general procedure.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06849650B2uspto-grants-2005_02