Reaktion #51356

ord-bc0b5b8ae5a74a449c064857efab9915

Reaktionsgleichung

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
→
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC(C)C
2-[(4-nitrophenyl)acetamido]butyric acid iso-butyl ester

Edukte

O=C(O)Cc1ccc([N+](=O)[O-])cc1
4-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe reaction was monitored by tlc on silica gel and purification
  2. 2
    Filtrationwas by filtration

Vorschrift

Following General Procedure BI above and using 4-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06849650B2uspto-grants-2005_02