Reaktion #5134

ord-c5ae183eb4bd4d98998488c4391b784a

Reaktionsgleichung

COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Compound h
COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Methyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate
c1ccc2[nH]cnc2c1
benzimidazole
c1ccc2[nH]ccc2c1
indole
→
COC(=O)c1ccc2c(c1)/C(=C/Cn1ccc3cccnc31)c1ccccc1CO2
Methyl (E)-11-[2-(7-aza-1-indolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

Edukte

COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Compound h
COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Methyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate
c1ccc2[nH]cnc2c1
benzimidazole
c1ccc2[nH]ccc2c1
indole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeIn Examples 40 through 49, the products were prepared in a manner similar to Example 23

Vorschrift

In Examples 40 through 49, the products were prepared in a manner similar to Example 23, using Compound h and the corresponding benzimidazole or indole derivatives.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05242931uspto-grants-1993_09