Reaktion #5129

Reaktionsgleichung

1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide

methanol water

→

guanidine

1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetate

Reaktionsbedingungen

Vorschrift

30.0 g (0.048 mol) of 1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide in 300 ml of methanol/water (1:1) were filtered through a column containing 250 g of ion exchanger (OH- form). The free guanidine base obtained after working up was dissolved in methanol and converted into the diacetate with excess glacial acetic acid.

Quelle