Reaktion #51276

Reaktionsgleichung

4-bromophenol

isobutylene

→

2-tert-butyl-4-bromophenol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeis passed through for 30 hours
2. 2
   TemperaturThe reaction mixture is cooled
3. 3
   Sonstigethe residue is purified
4. 4
   Wascheneluted with a mixture
5. 5
   Sonstige88.00 g (90%) of the expected compound are collected in the form of a yellow oil

Vorschrift

80.00 g (426.0 mmol) of 4-bromophenol and 8.00 g of Dowex 50WX8 sulphonic acid resin are mixed in a 250 ml three-necked flask. The mixture is heated to 80° C. and a stream of isobutylene is passed through for 30 hours. The reaction mixture is cooled and the residue is purified by passing through a silica column eluted with a mixture composed of 95% dichloromethane and of 5% heptane. 88.00 g (90%) of the expected compound are collected in the form of a yellow oil.

Quelle