Reaktion #512645

Reaktionsgleichung

1-bromopentane

4-bromoindole

benzyl 3-bromopropyl ether

isatin

→

title compound

1-[3-(benzyloxy)propyl]-1H-indole-2,3-dione

Reaktionsbedingungen

Vorschrift

Following the procedure as described in PREPARATION 1A, and making non-critical variations to replace 4-bromoindole with isatin, and 1-bromopentane with benzyl 3-bromopropyl ether, the title compound was obtained (95%) as a pale yellow syrup: 1H NMR (300 MHz, CDCl3) δ 7.57-6.92 (m, 9H), 4.50 (s, 2H), 3.84 (t, 2H), 3.54 (t, 2H), 2.03-1.94 (m, 2H); MS (ES+) m/z 296.3 (M+1), 318.3 (M+23).

Quelle