Reaktion #512424

Reaktionsgleichung

8-(4-bromo-2,6-dimethyl-phenyl)-2-methyl-4-(1-propyl-butylamino)-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid amide

HCl ethyl acetate

→

title compound

8-(4-bromo-2,6-dimethyl-phenyl)-2-methyl-4-(1-propyl-butylamino)-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid amide hydrochloride

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooling bath
2. 2
   EinengenThe resulting solution was concentrated under reduced pressure
3. 3
   SonstigeThe residue was crystallized from ethyl acetate

Vorschrift

To a suspension of 8-(4-bromo-2,6-dimethyl-phenyl)-2-methyl-4-(1-propyl-butylamino)-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid amide (5.8 g) in ethanol (30 mL) was added 4 M HCl/ethyl acetate (3.7 mL) in an ice-cooling bath. The resulting solution was concentrated under reduced pressure. The residue was crystallized from ethyl acetate to give the title compound.

Quelle