Reaktion #51230

Reaktionsgleichung

N-(tert-butoxycarbonyl)piperazine

potassium carbonate

hydrochloric acid

butyl iodide

→

N-butylpiperazine.dihydrochloride

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigereaction

Vorschrift

To a dimethylformamide (7 ml) solution containing N-(tert-butoxycarbonyl)piperazine (1.0 g) were added potassium carbonate (742 mg) and then butyl iodide (1.09 g), and the mixture was stirred at room temperature for 15 hours to undergo reaction, thereby obtaining N-tert-butoxycarbonyl-N-butylpiperazine. This compound was acid-treated with hydrochloric acid to obtain N-butylpiperazine.dihydrochloride.

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