Reaktion #51089

Reaktionsgleichung

2-amino-5-trifluoromethylpyridine

cyclohexyl isocyanide

furfural

acetyl chloride

→

Compound ( 34 )

N-cylcohexyl-N-(2-furan-2-yl-6-trifluoromethylimidazo[1,2-a]pyridin-3-yl)-acetamide

Lösungsmittel

perchloric acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeExcess acetyl chloride was removed under reduced pressure

Vorschrift

Compound (34) was prepared from 1.0 ml of 2-amino-5-trifluoromethylpyridine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of furfural solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%), and reaction with acetyl chloride. Excess acetyl chloride was removed under reduced pressure.

Quelle